Birdwatch Note Rating
2024-02-24 09:24:43 UTC - HELPFUL
Rated by Participant: 7CA6502492E068A7A56E0E655C780D6BD8D62CA21BEDB181565423BCDD15EF6A
Participant Details
Original Note:
Misleading Transfection of cancer cell lines MCF3 & OVCAR3 is known and understood https://pubmed.ncbi.nlm.nih.gov/7647336/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409137/ As rapidly dividing cell lines expressing retrotransposon LINE1, integration of transfected mRNA is to be expected https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067914/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749194/ There is no data to suggests this happens with primary human cells
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