Birdwatch Note Rating
2024-03-02 21:52:14 UTC - NOT_HELPFUL
Rated by Participant: 10EA55B843D092A3AC69CE6474F5B4961F724B65097BC81D74D23FA6CDDB45A2
Participant Details
Original Note:
Misleading Transfection of cancer cell lines MCF3 & OVCAR3 is known and understood https://pubmed.ncbi.nlm.nih.gov/7647336/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409137/ As rapidly dividing cell lines expressing retrotransposon LINE1, integration of transfected mRNA is to be expected https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067914/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749194/ There is no data to suggests this happens with primary human cells
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